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10.1001/jama.292.4.490 13 LindamoodC

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While the classical incretin concept is based on the assumption that incretin hormones such as GIP and GLP-1 reach their main endocrine target cells via the bloodstream, there is some evidence that GIP (and possibly GLP-1) can be produced in relatively small amounts in endocrine alpha-cells of the pancreas [3]

I also review how different feeding windows of 8 or 10 or 4 hours differentially impact the effects of fasting, and why the classic 8 hour feeding window came to be but also might be ideal